Standardization of Hemoglobin A1c

Another step toward standardization of methods for measuring hemoglobin A1c.

Measurement of Hemoglobin A1c

Evaluation of glycemia is used for the diagnosis and management of patients with diabetes. Glucose and hemoglobin A1c (HbA1c) provide complementary information and both are used to assess an individual’s glycemic status. The concentration of glucose in the blood indicates the subject’s glycemia at the time of blood sampling. However, blood glucose concentrations are modified by numerous factors...

Unexpected hemoglobin A1c results.

A 52-year-old woman with a medical history of hepatitis B, hyperlipidemia, hypertension, anemia, and depression presented to the internal medicine clinic for a routine visit. Laboratory tests 3 months previously had revealed an impaired fasting glucose concentration of 5.9 mmol/L (106 mg/dL) [reference interval, 3.9 –5.6 mmol/L (70 –100 mg/dL)]. Therefore, a hemoglobin (Hb) A1c analysis was per...

Standardization of method for determining glycosylated hemoglobin (Hb A1c) by cation exchange high performance liquid chromatography

Hemoblobin A1c is the most important parameter for the monitoring of metabolic control of patients with diabetes mellitus. The purpose of this study was to adapt the Mono S method to a conventional HPLC system, allowing highly selective HbA1c determination without the acquisition of kits or the use of dedicated systems The results obtained were compared to the Tinaquant® immune turbidimetric me...

Standardization of the hemoglobin A1c reporting: transferring global consensus to the local community--special report.

As so cia tion for the Stu dy of Dia be tes (EASD), In ter-na tio nal Dia ba tes Fe de ra tion (IDF), IFCC and In ter-na tio nal So cie ty for the Pe diat ric and Ado les ce nt Dia be tes (ISPAD) du ri ng the I DF-Wor ld Dia be tes Con gre ss in Mon treal, Ca na da, Oc to ber 2009.